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Searching the Biological Activity List

This search aid contains a controlled vocabulary of all biological activities assigned to compounds in the Index Chemicus database.

Find Option

  1. Enter a word in the text field. Wildcards (* ?) are permitted.

  2. Click the Find button to go to a list of codes that contain the characters that you entered. For example, entering Hydroxylase* finds every code in the index that contains this term regardless of where the term appears in the code.

  3. Click the Add button to add a code to the text box at the bottom of the page.

  4. Click OK to transfer the selected item(s) to the search page.

Try searching for the same or related activities in more than one way. For example, if you are interested in compounds with anticarcinogenic activity, search for:

  • anticarcin*
  • carcin*
  • antineop*

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Selecting Multiple Terms from the Biological Activity List

If you select multiple terms from the search aid, then you may need to enclose those terms within quotation marks when you return to the Structure Search page. For example, let us assume that you have selected the following terms.

TYROSINE HYDROXYLASE ACTIVATING ACTIVITY OR TYROSINE HYDROXYLASE INHIBITING ACTIVITY OR STEROID 11-BETA-HYDROXYLASE INHIBITING ACTIVITY

If you run this search, the product displays an error message informing you that it cannot find any records that match this query.

However, if you enclose the terms within quotation marks, the product returns records that match the query. For example:

"TYROSINE HYDROXYLASE ACTIVATING ACTIVITY" OR "TYROSINE HYDROXYLASE INHIBITING ACTIVITY" OR "STEROID 11-BETA-HYDROXYLASE INHIBITING ACTIVITY"

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Examples

If you enter Cardi* you will find these biological activities:

  • CARDIAC ACTIVITY
  • CARDIOTONIC ACTIVITY
  • CARDIOTOXIC ACTIVITY
  • CARDIOVASCULAR ACTIVITY

if you enter Hydroxylase* you will find these biological activities:

  • DOPAMINE BETA-HYDROXYLASE INHIBITING ACTIVITY
  • HYDROXYLASE INHIBITING ACTIVITY
  • KYNURENINE 3-HYDROXYLASE INHIBITING ACTIVITY
  • And more ...
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